1. Lamotrigine is considered a first-line agent for the treatment of bipolar depression . 2. The majority of antidepressants appear ineffective in treating bipolar depression . 3. It has not been extensively studied in bipolar depression . 4. They are ineffective in treating acute bipolar depression , preventing relapse, and can cause rapid cycling. 5. Zonisamide ( trade name Zonegran ), another anti-convulsant, also may show promise in treating bipolar depression . 6. Suffering from bipolar depression , she separated from her husband in 1977 and became a much-talked-about jet-setter. 7. MAOIs appear to be particularly effective in the management of bipolar depression according to a recent retrospective-analysis. 8. Jenny "'- A song written about Jonny Hawkin s sister, Jenna; who struggles with bipolar depression everyday. 9. Lamotrigine has some efficacy in treating bipolar depression , and this benefit is greatest in more severe depression. 10. This study demonstrates a rapid-onset antidepressant effect of ketamine in a small group of patients with bipolar depression .